Our Staff
Our Office
   Digital Radiology
New Patients
TMJ Therapy
Other Services
   Cosmetic Dentistry
   Oral Sedation
   Sleep Disorders
   Teeth Whitening
   Root Canal
   Jaw Orthopedics
General Health Topics
Post Treatment Guidelines
Visit Us

Osteonecrosis of the Jaw (ONJ)

Osteonecrosis of the Jaw (ONJ)

Newsletter for November, 2006

Dear Patients,

As the temperatures turn south and the whitish form of precipitation begins to fall, the mind fills with thoughts of the holidays and family get-togethers.

Sometimes, when a new prescription drug is introduced to the market it comes with some side effects. Generally, the positive benefits of the drug outweigh the potential negatives. Sometimes these rare side effects can be life threatening or even fatal. This is the case with bisphosphonates. These drugs were introduced in the mid 1990's to help treat osteoporosis. The most common side effects included esophageal irritation, stomach upset, and muscle or bone discomfort. Recently it has been revealed that these drugs can also produce a rare but serious and often untreatable side effect, osteonecrosis of the jaw (ONJ). 

ONJ reduces the entire jaw to abscess and it gradually rots away. Surgical removal of the affected jaw is sometimes necessary to save the patients life, otherwise death from organ failure results. The most popular drug names are Fosamax and Actonel. The literature cites that any procedure that exposes the bone in the oral cavity places the patient at high risk for ONJ. Traumatic dental procedures like extractions, periodontal surgery, endodontic surgery, and implant placement may precipitate the onset of ONJ. There are even documented cases of ill-fitting dentures/partials causing ulcerations which have lead to ONJ. The predominate opinion by the experts recommends that any patient considering biphosphonate therapy should be examined by a dentist and have any invasive dental procedures performed prior to the initiation of the therapy.

If you or someone you love is presently taking a biphosphonate or considering biphosphonate therapy, please contact our office for a no-charge consultation.


Michael W. Dagostino, DDS

Cick here for printer friendly version




Sleep Apnea


Pediatric Anesthetic
Tourette’s syndrome
Dental Hygiene Importance


Our sophisticated dental office offers digital radiography, sterilization, nitrous oxide (laughing gas) and many other up-to-date features to offer you comfort and convenience while we provide superior service and quality dental services




Dr. Michael Dagostino, D.D.S.
6887 Ridge Road
Parma, Ohio 44129
Telephone: (440) 842-2171

Join our mailing list by clicking on the register link below.